LPS‐induced TNFα production by macrophages is suppressed by a soluble product from the adult tapeworm, Hymenolepis diminuta

New Data on Human Macrophages Polarization by Hymenolepis diminuta Tapeworm—An In Vitro Study

Helminths and their products can suppress the host immune response to escape host defense mechanisms and establish chronic infections. Current studies indicate that macrophages play a key role in the immune response to pathogen invasion. They can be polarized into two distinct phenotypes: M1 and M2. The present paper examines the impact of the adult Hymenolepis diminuta (HD) tapeworm and its ex...

Thymus dependence of tapeworm (Hymenolepis diminuta) elimination from mice.

Although normal mice eliminated the lumen-dwelling intestinal cestode Hymenolepis diminuta by day 21 post-cysticercoid inoculation, congenitally thymus-deficient (nude) mice maintained their work burdens. Nude mice grafted with thymus glands or injected with thymus cells eliminated their worms.

Identification of an NAD-dependent 3-acetamidobenzamide-sensitive system in oncospheres from the tapeworm Hymenolepis diminuta.

( a ) Autoradiograph of RNA species which arise in a transcription reaction. Nomenclature, fragment sizes and experimental conditions are as in 141. RNA circles are arrowed wth their tentative sizes in nucleotides. Precursor (p), ribozyme (IVS), ligated exons (SE3E) and precursor in which the downstream exon has been hydrolysed (5EI) are depicted. ( b ) Autoradiograph of radiolabelled amplified...

Studies on Malic Enzyme from Hymenolepis Diminuta

Establishment Success of the Beetle Tapeworm Hymenolepis diminuta Depends on Dose and Host Body Condition

Parasite effects on host fitness and immunology are often intensity-dependent. Unfortunately, only few experimental studies on insect-parasite interactions attempt to control the level of infection, which may contribute substantial variation to the fitness or immunological parameters of interest. The tapeworm Hymenolepis diminuta-flour beetle Tenebrio molitor model-has been used extensively for...